Lymphocyte Activation in Cutaneous Drug Reactions
نویسندگان
چکیده
منابع مشابه
Lymphocyte activation in cutaneous drug reactions.
Peripheral blood lymphocytes from both drug-induced immediate and delayed cutaneous hypersensitivity reactions frequently can be stimulated in vitro with the particular culprit drug. Immunohistochemical analysis has identified CD8+ T cells as the predominant epidermal T-cell subset in drug-induced maculopapular and bullous eruptions and in patch-test reactions to beta-lactam antibiotics. Beta-l...
متن کاملCutaneous drug reactions.
Cutaneous drug reactions are the most frequently occurring adverse reactions to drugs. Among hospitalized patients, the incidence of these reactions ranges from 1 to 3%. The frequency of cutaneous reactions to specific drugs may exceed 10%. These reactions may range from mildly discomforting to those that are life-threatening. Anti-infective and anticonvulsant agents are among the drugs most co...
متن کاملAdverse cutaneous drug reactions
| August 2014 | 798 Finally, the authors detected a higher prevalence of more serious and life-threatening types of ACDR like Stevens Johnson and toxic epidermal necrolysis in their study. This finding is so important and may be due to the difference in type and potency of metabolic pathways in Iranian patients due to their ethnic groups, or it may be due to not including the above mentioned ri...
متن کاملCutaneous drug reactions in children.
Brandon Newell, MD, is Assistant Professor; and Kimberly A. Horii, MD, is Associate Professor, University of Missouri-Kansas City, Children’s Mercy Hospitals and Clinics. Address correspondence to: Brandon D. Newell, MD, of Missouri-Kansas City, Children’s Mercy Hospitals and Clinics, 2401 Gilham Road, Kansas City, MO 64108; fax: 816-983-6710; or e-mail: [email protected]. Dr. Newell and Dr. Hori...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 1995
ISSN: 0022-202X
DOI: 10.1038/jid.1995.19